Silicone hydrogel contact lens wear shows no significant change in corneal sensitivity
New wearers of silicone hydrogel contact lenses showed no significant changes in corneal sensitivity over the first 6 weeks, and no significant association was found between corneal sensitivity and contact lens comfort, according to a study.
Corneal sensitivity in the right eye was measured at each visit using the Swiss Liquid Jet Aesthesiometer for Corneal Sensitivity. Contact lens comfort was evaluated at the second and third visits using the Contact Lens Dry Eye Questionnaire (CLDEQ-8). A total of 38 participants completed the study.
Overall, no significant differences in corneal sensory threshold were found across the 3 visits. However, changes in corneal sensitivity differed by gender, with females showing a decreasing trend and males an increasing trend over time. No significant correlations were identified between corneal sensitivity and contact lens comfort after either 1 week or 6 weeks of wear.
The findings indicate that short-term adaptation to silicone hydrogel contact lenses did not result in measurable changes in corneal sensitivity, although gender-related differences in sensory response were observed.
Reference
Seghetti M, Nosch DS, Albon J. Corneal sensitivity in new silicone hydrogel contact lens wearers. Cont Lens Anterior Eye. 2026;49(2):102607. doi: 10.1016/j.clae.2026.102607. Epub ahead of print. PMID: 41558082.
